规格 / Specification

应用 / Applications

DPPF二氯化钯是一种独特的含铁配体-dppf的钯络合物，该催化剂因其在实现复杂分子结构构建方面的卓越性能，成为现代有机合成中不可或缺的工具。

DPPF二氯化钯最主要的功能是作为高效催化剂，广泛应用于各种钯催化偶联反应，特别是交叉偶联反应，从而实现关键的碳-碳键(C-C)和碳-氮键(C-N)形成。

(DPPF)PdCl2 is a unique palladium complex containing the iron ligand -dppf. This catalyst has become an indispensable tool in modern organic synthesis due to its superior performance in achieving complex molecular structures.

The primary function of (DPPF)PdCl2 is as a highly efficient catalyst, widely used in various palladium-catalyzed coupling reactions, especially cross-coupling reactions, to achieve the formation of crucial carbon-carbon (C-C) and carbon-nitrogen (C-N) bonds.

When applied to Grignard cross-coupling, (DPPF)PdCl2 effectively catalyzes the coupling reactions between haloalkenes, haloaromatics, or trifluoromethanesulfonic acid-based aromatics and Grignard reagents. Compared to traditional palladium catalysts, (DPPF)PdCl2 effectively suppresses the formation of isomerization and reduction byproducts.

(DPPF)PdCl2 is ideally suited for the Stille and Suzuki reactions, particularly for the cross-coupling of vinyltin with aryltrifluoromethanesulfonic acid and the reaction of aryltin with aryltrifluoromethanesulfonic acid under a CO atmosphere, efficiently yielding aryl ketone compounds.

(DPPF)PdCl2 is also used as an important catalyst in carbonylation reactions.

The unique structure of (DPPF)PdCl2 endows it with distinctive activation capabilities, making it excellent in reactions where conventional palladium catalysts are ineffective:

In the activation of organosulfides, (DPPF)PdCl2 enables cross-coupling between methyl sulfides and aryl Grignard reagents, overcoming the challenge of activating organosulfur compounds with conventional Pd catalysts.

In iodine-zinc exchange reactions, (DPPF)PdCl2 effectively catalyzes the iodine-zinc exchange reaction, thereby achieving intramolecular carbon-zincification of olefins.

In hydrogen esterification reactions, (DPPF)PdCl2 is used for the hydrogen esterification of trimethylsilylalkyne to yield conjugated vinylsilyl compounds.

The excellent properties of (DPPF)PdCl2 have led to its wide application in several high-tech and fine chemical fields:

In pharmaceutical chemistry, (DPPF)PdCl2 serves as a key catalyst for the preparation of various complex organic molecules, including nucleoside synthesis as an inhibitor of exonucleases.

In organic chemistry, (DPPF)PdCl2 is used for the efficient and selective construction of C-C and C-N skeletons in fine organic synthesis.

In the synthesis of liquid crystal materials, (DPPF)PdCl2 plays a crucial role in the chemical synthesis of liquid crystal materials.

包装 / Packing

1/10/25kgs/drum

运输编号 / UN number

普通化学品 / Not dangerous goods

储存条件 / Store at

密封保存于阴凉干燥处，避光避热。 / Sealed storage in a cool and dry place, avoid light and heat.

保质期 / Shelf Life

两年 / Two years