规格 / Specification

应用 / Applications:

二叔丁基苯基膦是一种极具应用价值的有机膦配体。由于其分子结构中含有两个体积巨大的叔丁基以及一个苯基，赋予了该分子显著的空间位阻效应和极强的电子密度。这种“富电子、大位阻”的特性使其在过渡金属催化领域，尤其是钯催化的偶联反应中表现出卓越的催化活性和选择性。该产品通常为对空气和湿气敏感的液体，需在惰性气体保护下储存，广泛服务于高端医药合成、精细化工及新型功能材料的研发。

Di-tert-butylphenylphosphine is a highly valuable organophosphine ligand. Its molecular structure, containing two bulky tert-butyl groups and a phenyl group, endows it with significant steric hindrance and extremely high electron density. This "electron-rich, sterically hindered" characteristic makes it exhibit excellent catalytic activity and selectivity in transition metal catalysis, particularly in palladium-catalyzed coupling reactions. This product is typically a liquid sensitive to air and moisture and must be stored under an inert gas atmosphere. It is widely used in high-end pharmaceutical synthesis, fine chemicals, and the research and development of novel functional materials.

1. In the pharmaceutical intermediate synthesis industry, di-tert-butylphenylphosphine is mainly used as a key ligand in Buchwald-Hartwig coupling reactions. By enhancing the electron density of the palladium central atom, it can greatly promote the catalytic reaction of aryl halides with amines, thereby efficiently constructing carbon-nitrogen bonds for the synthesis of complex active fragments in antitumor and antiviral drugs.

2. Di-tert-butylphenylphosphine is widely used in the production of pesticide chemicals for the development of various novel herbicides and fungicides. It exhibits excellent performance in the Suzuki coupling reaction, assisting the catalyst in completing the connection between arylboronic acids and aryl halides at lower temperatures, shortening the production cycle and reducing byproduct generation.

3. In the field of fine chemical catalysis, di-tert-butylphenylphosphine serves as a highly efficient stabilizer and auxiliary agent for the preparation of high-performance homogeneous catalysts. Its unique steric hindrance structure effectively prevents the formation of palladium black precipitate, extending catalyst lifespan and significantly reducing catalyst costs in industrial production.

4. In the organic light-emitting diode (OLED) manufacturing industry, di-tert-butylphenylphosphine is used to synthesize novel optoelectronic materials. By participating in the catalytic carbon-carbon bond coupling reaction, it helps construct high-purity polycyclic aromatic hydrocarbon or heterocyclic compound frameworks, which are core raw materials for improving the luminous efficiency and lifespan of displays.

5. Di-tert-butylphenylphosphine is frequently used as an important member of the ligand library in academic research and laboratory analysis to explore novel metal-organic frameworks (MOFs) or study the coordination chemistry of transition metals. Its well-defined electronic regulation capabilities make it a preferred research reagent for developing novel and efficient chemical reaction pathways.

包装 / Package:

25/50/100/200/Cylinder

运输编号 / UN number:

UN 2845 4.2/PG I

储存条件 / Store at:

密封保存于5℃以下阴凉干燥处，避光避热。 / Keep container tightly sealed. Store in a cool, dry place below 5°C. Protect from light and heat.

保质期 / Shelf Life:

一年 / One year