- Product Name:
- N,N,N',N'-Tetramethylchloroformamidinium hexafluorophosphate
- CAS No:
- 207915-99-9
- EC No:
- 627-919-5
- Synonyms:
- CHLORO-N,N,N,N-TETRAMETHYLFORMA-MIDINIUM PF6;Chloro-N,N,N',N'-tetramethylformamidiniumhexafluo;N,N,N',N'-Tetramethylchloroformamidinium-hexafluorophosphate;N-(Chloro(diMethylaMino)Methylene)-N-MethylMethanaMiniuM hexafluorophosphate(V);
N,N,N',N'-Tetramethylchloroformamidinium hexafluorophosphate, TCFH reagent, CAS 207915-99-9, peptide coupling reagent, Suzhou Health Chemicals, TCFH manufacturer, amidation reagent for hindered carboxylic acids, esterification coupling reagent, Chloro-N,N,N',N'-tetramethylformamidinium hexafluorophosphate, high purity TCFH bulk supply, solid phase peptide synthesis reagents, onium salt coupling agent, CAS 94790-35-9
N,N,N',N'-Tetramethylchloroformamidinium hexafluorophosphate, TCFH reagent, CAS 207915-99-9, Chloro-N,N,N',N'-tetramethylformamidinium hexafluorophosphate, peptide coupling agent, Suzhou Health Chemicals
Product Introduction
N,N,N',N'-Tetramethylchloroformamidinium hexafluorophosphate (TCFH) is predominantly utilized as a highly efficient coupling reagent in peptide synthesis (both SPPS and LPPS) and pharmaceutical chemical synthesis. It showcases outstanding performance in constructing difficult amide bonds involving highly sterically hindered carboxylic acids and low-nucleophilic amines or alcohols. TCFH serves as an economical and high-yield alternative for generating esters, thioesters, and ketones, making it a staple reagent in modern drug discovery and commercial chemical manufacturing.
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