- Product Name:
- N,N,N',N'-Tetramethylchloroformamidinium hexafluorophosphate; TCFH
- CAS No:
- 94790-35-9
- EC No:
- 680-115-6
- Synonyms:
- N,N,N',N'-TETRAMETHYLCHLOROFORMAMIDINIUM HEXAFLUOROPHOSPHATE;TCFH;TCFH N,N,N,N-TETRAMETHYLCHLOROFORMAMIDINIUM-HEXAFLUOROPHOSPHATE;N,N,N'',N''-TETRAMETHYLCHLOROFORMAMIDINIUM HEXAFLUOROPHOSPHATE (TCFH);tetramethyluronium hexafluorophosphate;N,N,N',N'-Tetramethylchloroformamidinium hexafluorophosphate (TC;N-[Chloro(dimethylamino)methylene]-N-methyl-methanaminium;N,N,N',N'-Tetramethylchloroformamidinium-hexafluor
N,N,N',N'-Tetramethylchloroformamidinium hexafluorophosphate, 94790-35-9, TCFH coupling reagent, TCFH peptide synthesis, Chloroformamidinium reagent, Amide bond formation, Chloroformamidinium hexafluorophosphate, Suzhou Health Chemicals, High purity TCFH manufacturer, Peptide coupling reagent TCFH, TCFH CAS 94790-35-9, Pharmaceutical intermediates, Organocatalyst TCFH, Sterically hindered peptide synthesis, TCFH supplier China, Chemical reagent exporter
N,N,N',N'-Tetramethylchloroformamidinium hexafluorophosphate, TCFH reagent, 94790-35-9, Peptide coupling reagent, Suzhou Health Chemicals
Product Introduction
N,N,N',N'-Tetramethylchloroformamidinium hexafluorophosphate (TCFH) is a highly efficient, non-hygroscopic chloroformamidinium-based peptide coupling reagent. It is primarily utilized for the activation of carboxylic acids to form amide bonds under mild conditions. TCFH demonstrates exceptional reactivity and low racemization rates, making it particularly effective for sterically hindered amino acid couplings, SPPS of N-methylated peptides, and esterification reactions. It serves as a cost-effective alternative to traditional coupling reagents in pharmaceutical synthesis.
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