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  • Suzhou Health Chemicals Co., Ltd.
  • Tel : +86-512-58277800
  • FAX : +86-512-58999904
  • Address : No. 338, Jingang Avenue, ZhangJiaGang City, Jiangsu Province, China.
  • P.C. : 215600
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ProductsDetails

Product Name:
Polydeoxyribonucleotide; PDRN
CAS No:
9015-85-4
EC No:
232-770-0
Synonyms:
Polydeoxyribonucleotide (Adenosine Triphosphate);T4 DNA LIGASE;Synthetase, polydeoxyribonucleotide

Product Introduction

规格 / Specification

项目 / Item

标准(食品级、化妆品级、医药级、医疗器械级)

Standards (Food Grade, Cosmetic Grade, Pharmaceutical Grade, Medical Device Grade)

外观 / Appearance

白色至类白色粉末或纤维聚合物、颗粒 / White to off-white powder or fiber polymer, granular

气味 / Odor

典型 / Characteristic

鉴定 / Identification

IR/HPLC/Mass/NMR Spectrum

纯度 / Purity (UV)

99.0%

pH

6.0~8.0

溶解性 / Solubility

水溶 / Water soluble

原料来源 / Source

雄性鲑鱼精巢 / Salmon sperm sac


功效 / Functions

渔夫用三文鱼精巢里的精液涂抹伤口,经过专家学者的研究,发现了三文鱼体内的PDRN成分。

A fisherman applied semen from salmon testes to his wound, and following research by experts and scholars, the PDRN component in salmon was discovered.

A long time ago, a fisherman suffered a severe injury to his arm while working at sea. Medical facilities were inadequate at the time, and his wound festered and would not heal. The fisherman could only try a remedy passed down through his ancestors, squeezing semen from salmon testes and periodically applying it to his wound. Day after day, the fisherman noticed that his wound not only did not continue to fester but also healed completely. Later, following research by experts and scholars, the PDRN component in salmon was discovered.


PDRN是存在于人体胎盘中的核酸混合物,是细胞内生成DNA原料的复合体之一。

PDRN is a mixture of deoxyribonucleotides found in human placenta and is one of the complexes that serve as raw materials for DNA synthesis within cells. PDRN has a unique ability to promote recovery after skin transplantation, and after being approved in 2008, was first used as a tissue repair compound in Italy. In recent years, due to the remarkable effects of PDRN in cosmetics, PDRN mesotherapy has become one of the most popular techniques in Korean dermatology clinics and plastic surgery centers. As a cosmetic and pharmaceutical raw material, PDRN is widely used in fields such as medical aesthetics, daily chemical products, medical devices, health foods, and pharmaceuticals. The PDRN we offer is a mixture of deoxyribonucleotides extracted from salmon testes. Its base composition has a similarity of up to 98% with human DNA.


PDRN的作用机制:

Mechanism of Action of PDRN:

1: PDRN binds to adenosine A2A receptors, initiating multiple signaling pathways to increase anti-inflammatory factors, reduce inflammatory factors, and inhibit inflammatory responses.

2: PDRN promotes fibroblast proliferation and the secretion of EGF, FGF, and IGF, remodeling the internal environment of damaged skin.

3: PDRN promotes VEGF production to generate capillaries, supplying nutrients for skin repair and removing aged substances.

4: PDRN, through the salvage pathway, provides purines or pyrimidines, accelerating DNA synthesis to promote rapid skin regeneration.


应用 / Applications

PDRN的优点:安全性、稳定性、功能性、有效性。

PDRN Advantages:

Safety: This raw material product is a non-toxic and non-irritating safe substance.

Stability: This raw material product increases the elasticity of the epidermis and dermis and is thermally stable.

Functionality: Repairs cells from DNA damage induced by ultraviolet radiation and skin irritation, and promotes DNA repair.

Effectiveness: By cutting DNA into certain active fragments, it repairs the underlying muscle layer from within and repairs the skin barrier from the outside.


PDRN stimulates skin cells to rapidly secrete cell growth factors, promoting collagen production. PDRN promotes damaged tissue regeneration, has anti-inflammatory properties, rejuvenates the skin, and enhances skin elasticity. PDRN can inhibit melanin production and is effective in treating diabetic foot ulcers.

PDRN has regenerative effects, improves skin elasticity, enhances skin tone and texture, has anti-aging and anti-wrinkle properties, eliminates acne scars, and promotes skin regeneration. PDRN has a wide range of applications and can be added to various skincare products, such as cleansers, toners, creams, serums, lotions, masks, and BB creams. PDRN is used in lotions, creams, serums, masks, and other products for regeneration and anti-wrinkle effects. PDRN is used in repair lotions and antibacterial ointments for repair and anti-inflammatory effects. PDRN is used in acne scar cold compresses, scar patches, and wound healing gels for scar and acne pit removal. PDRN is also used in shampoos for hair loss prevention, promoting the regeneration of healthy hair follicle tissue.



祛皱功效 Anti-wrinkle effects / Wrinkle reduction effects



祛痘功效 Anti-acne effects / Acne reduction effects



祛疤痕功效 Anti-scarring effects / Scar reduction effects



再生修复功效 Regenerative and reparative effects / Regeneration and repair effects



用于宠物医药,治疗宠物皮肤疾病、关节疾病、眼科疾病等。
Can be used in veterinary medicine to treat pet skin diseases, joint diseases, ophthalmic diseases, etc.


推荐使用量 / Recommended use level

PDRN适合添加量:0.02%~2%

1: Recommended PDRN addition level: 0.02% to 2%.

2: PDRN dissolution: PDRN generally dissolves faster in a 50°C water bath. Increasing the temperature accelerates dissolution, but excessive heat can degrade its molecular weight.

3: Suitable thickeners for PDRN: Xanthan gum, sodium hyaluronate (1% solution).

4: Emulsification: Surfactants with an HLB value greater than 9 are recommended for optimal emulsification with PDRN.

5: Preservation: Establish a composite preservative system for PDRN, which can include combinations like butylene glycol with pentylene glycol.

6: Incompatible ingredients: Strong oxidizing agents, highly reactive substances, and cationic salts.

包装 / Packing

1/10/25kgs/drum


运输编号 / UN number

普通化学品 / Not dangerous goods


储存条件 / Store at

密封保存于阴凉干燥处,避光避热 / Sealed storage in a cool and dry place, avoid light and heat.


保质期 / Shelf Life

两年 / Two years



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